Product Introduction
- Product Overview: The Saliva Collection Kits developed by Xiamen Zhizi Industry & Trade Co., Ltd. are professional medical devices designed for non-invasive collection and preservation of saliva samples. Widely used in nucleic acid detection (e.g., COVID-19 testing), genetic testing, and clinical research, these kits replace traditional invasive nasopharyngeal swab sampling methods. Each Saliva Collection Kits integrates a collection tube, special preservation solution, filtration component, and disposable accessories, providing a one-stop solution for saliva sample processing. With their user-friendly design, high sample stability, and wide compatibility, they are favored by hospitals, 体检 centers, and research institutions, effectively improving sampling efficiency and subject compliance.
- Product Performance: The Saliva Collection Kits excel in sample preservation and usability. The pre-filled saliva-specific preservation solution contains nuclease inhibitors and proteinase K, which can maintain nucleic acid stability for up to 14 days at 2-25℃, with a nucleic acid detection rate of over 99%. The 0.22μm sterile filter membrane in the kit removes mucus and cell debris from saliva, avoiding interference with subsequent detection. The collection tube features a 22mm wide-mouth curved nozzle for easy saliva collection, and an anti-reflux valve prevents sample spillage. Additionally, the standardized 12mm diameter tube is compatible with mainstream nucleic acid extractors (e.g., Thermo Fisher, Qiagen) and PCR instruments, eliminating the need for sample transfer and reducing human error.
2. Product Advantages
- Non-Invasive and Painless Design to Improve Subject Compliance: The Saliva Collection Kits adopt a "non-invasive saliva collection" solution, completely eliminating the discomfort of traditional nasopharyngeal swab sampling. The collection tube in the kit is equipped with a "wide-mouth curved nozzle" with a diameter of 22mm, which conforms to the physiological structure of the human oral cavity. Subjects do not need special cooperation and only need to spit saliva naturally to complete sampling—there is no stinging or foreign body sensation throughout the process. This design is particularly suitable for sensitive groups such as children, the elderly, and people with pharyngitis (those with sore throats or sensitive throats). Meanwhile, the surface of the nozzle is treated with anti-slip frosting, ensuring a stable grip even when hands are wet. The built-in "anti-reflux valve" prevents saliva samples from spilling during transportation, which not only improves the subject's experience but also reduces the risk of sample contamination. Compared with traditional swab sampling, this design increases subject compliance by more than 60%, significantly reducing sampling resistance (e.g., children no longer cry during sampling, and the elderly cooperate more actively).
- Sample Preservation System to Ensure Accurate Nucleic Acid Detection: The Saliva Collection Kits build a "dual sample protection mechanism" to ensure the stability and integrity of nucleic acid components in saliva. First, the collection tube is pre-filled with "saliva-specific preservation solution" containing components such as nuclease inhibitors and proteinase K. This preservation solution can quickly inhibit the activity of nucleases produced by bacteria in the oral cavity, preventing RNA/DNA degradation. Experimental verification shows that samples stored in the Saliva Collection Kits can remain stable for up to 14 days at 2-25℃, and the nucleic acid detection rate still remains above 99%—even in high-temperature environments (up to 25℃), there is no significant reduction in detection accuracy. Second, the kit is equipped with a "sample filtration component" with a sterile filter membrane of 0.22μm pore size. This filter membrane can effectively filter impurities such as mucus and cell debris in saliva, avoiding interference with subsequent nucleic acid extraction and PCR detection (e.g., preventing impurities from clogging the extractor's pipette tips or affecting fluorescent signal reading). In addition, the preservation solution uses a "low-toxicity formula" and has passed biocompatibility tests—there is no skin irritation or sensitization, which not only ensures sample quality but also reduces the risk of operation for medical staff (no need to worry about skin damage when contacting the preservation solution).
- Ready-to-Use & Full-Process Compatibility to Simplify Operation and Improve Detection Efficiency: The Saliva Collection Kits adopt an "integrated ready-to-use" structure, realizing convenient connection of the entire process from sampling to preservation to detection. Each kit contains all necessary consumables: collection tube (with pre-filled preservation solution), filtration component, sealed cap, and disposable gloves—there is no need to prepare additional tools, and the kit can be used immediately after opening the package. After sampling, subjects only need to screw the collection tube tightly; the preservation solution will automatically mix with saliva, and there is no need to manually add reagents (simplifying the operation steps for untrained personnel, such as community volunteers). At the same time, the collection tube adopts a "standardized size design" with a diameter of 12mm and a height of 100mm, which can be directly compatible with mainstream nucleic acid extractors (e.g., Thermo Fisher KingFisher, Qiagen QIAcube) and PCR instruments on the market. There is no need to transfer samples or replace containers, which reduces human operation steps (e.g., avoiding sample loss during transfer) and shortens the detection cycle by 30%. In addition, the kit supports "batch packaging and labeling"—each collection tube has a reserved writable information area where sampling time, name, and serial number can be marked directly with a marker pen. This is suitable for large-sample-volume collection scenarios such as hospitals, physical examination centers, and research institutions, significantly improving the efficiency of the detection process.
3. Product Application Scenarios
- Pediatric Medical Testing: In pediatric hospitals or pediatric departments, the Saliva Collection Kits are widely used for nucleic acid testing of children. Children are often resistant to invasive swab sampling, but the Saliva Collection Kits’ non-invasive design allows children to complete sampling by simply spitting saliva, avoiding crying and resistance. Nurses use the Saliva Collection Kits to collect samples quickly, and the Saliva Collection Kits’ sample preservation solution ensures stable nucleic acid until detection. Every day, pediatric hospitals use the Saliva Collection Kits for dozens of children, and the Saliva Collection Kits have become an essential tool for pediatric testing. Without the Saliva Collection Kits, pediatric sampling would be time-consuming and difficult.
- Community Large-Scale Screening: During community large-scale nucleic acid screening, the Saliva Collection Kits play a key role. Volunteers distribute the Saliva Collection Kits to residents, who can operate the Saliva Collection Kits independently (no professional training required). The Saliva Collection Kits’ ready-to-use design reduces volunteer workload, and the anti-reflux valve prevents sample spillage during collection. After sampling, the Saliva Collection Kits are centrally transported to laboratories, and their compatibility with extractors speeds up detection. In every community screening event, hundreds of Saliva Collection Kits are used, and the Saliva Collection Kits ensure efficient and smooth screening. The Saliva Collection Kits have become a reliable choice for community public health work.
- Scientific Research Experiments: In biological research institutions, the Saliva Collection Kits are used for collecting saliva samples in genetic research, microbiome analysis, etc. Researchers use the Saliva Collection Kits to collect samples from participants (e.g., for studying genetic variations or oral microbiota). The Saliva Collection Kits’ 14-day sample stability allows long-distance sample transportation, and the filtration component ensures pure samples for analysis. In every research project, the Saliva Collection Kits are used repeatedly, and the Saliva Collection Kits’ accuracy guarantees reliable research data. The Saliva Collection Kits provide strong support for scientific research progress.
4. Frequently Asked Questions
- Q: How should the Saliva Collection Kits be stored before use?
A: The Saliva Collection Kits should be stored in a cool, dry environment at 2-30℃, away from direct sunlight and high temperatures (avoid storage in cars in summer). Unopened kits have a shelf life of 18 months; once opened, use the kits within 24 hours to prevent contamination of accessories (e.g., gloves, filters).
- Q: Can the Saliva Collection Kits be used for testing other pathogens besides COVID-19?
A: Yes, the Saliva Collection Kits are suitable for nucleic acid detection of various pathogens (e.g., influenza virus, respiratory syncytial virus) and genetic testing (e.g., ancestry testing, disease susceptibility gene detection). The preservation solution’s ability to stabilize nucleic acids is applicable to most RNA/DNA samples, but it is recommended to confirm compatibility with specific detection reagents before use.
- Q: Is there an age limit for using the Saliva Collection Kits?
A: The Saliva Collection Kits are suitable for people aged 3 and above. For children under 3 years old (who cannot spit saliva independently), it is recommended to use the kit under the guidance of a doctor (e.g., collecting saliva with a sterile cotton swab and then transferring it to the collection tube). There is no upper age limit, and the elderly can easily use the kits due to their non-invasive design.
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